- Contact Person : Mr. Zhao Anson
- Company Name : Shaanxi Pioneer Biotech Co., Ltd.
- Tel : 86-29-88598270
- Fax : 86-29-84385017
- Address : Shaanxi,Xi'an,No 11. DQ Road
- Country/Region : China
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Levomefolic acid Levomefolic acid (INN) (also known as 5-MTHF, l-methylfolate and 5-methyltetrahydrofolate) is the natural, active form of folic acid used at the cellular level for DNA reproduction, the cysteine cycle and the regulation of homocysteine among other functions. The un-methylated form, folic acid (vitamin B9), is a synthetic form of folate found in nutritional supplements. Synthetic folic acid is metabolized in the body into levomefolic acid. Approximately 10% of the general population (homozygous TT) lack the enzymes needed to receive any benefit from folic acid Another 40% of the population (heterozygous CT) appear to convert only a limited amount of folic acid into levomefolic acid.
They cannot fully process supplemental folic acid at RDA or higher dose levels. The remaining population do not have a known MTHFR polymorphism and can therefore metabolize folic acid more efficiently.
It is synthesized in the absorptive cells of the small intestine from polyglutamylated dietary folate.
Levomefolic acid is a methylated derivate of tetrahydrofolate (THF, H4F). Levomefolic acid is generated by methylenetetrahydrofolate reductase (MTHFR) from 5,10-methylenetetrahydrofolate (5,10-CH2-THF, MTHF) and used to recycle homocysteine back to methionine by 5-methyltetrahydrofolate-homocysteine methyltransferase (MTR) also known as methionine synthase
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007 | Raspberry Ketone | Raspberry | 99% | USP32 | Drum & Bag |
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